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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Marcos Medina | 12 | 2025-2037 | |
| 2 | Luis Reyes | 10 | 2019-2026 | |
| 2 | Luis Valenzuela | 10 | 2022-2036 | |
| 4 | Cody Lee | 9 | 2029-2037 | |
| 4 | Jesús Ramos | 9 | 2024-2042 | |
| 4 | Jesús Ángel | 9 | 2018-2032 | |
| 7 | Carlos Elías | 8 | 2039-2047 | |
| 7 | Abel Gibson | 8 | 2029-2036 | |
| 7 | Santiago Pérez | 8 | 2034-2044 | |
| 7 | Esteban Sánchez | 8 | 2029-2041 | |
| 7 | José Sánchez | 8 | 2018-2030 | |
| 12 | Don Castor# | 7 | 2046-2053 | |
| 12 | Gord Downie | 7 | 2029-2034 | |
| 12 | Tim Humphrey | 7 | 2026-2029 | |
| 12 | José Olvera | 7 | 2023-2038 | |
| 12 | Adrián Salazar | 7 | 2020-2026 | |
| 12 | Rob Snyder | 7 | 2029-2032 | |
| 18 | Kip Foley | 6 | 2027-2033 | |
| 18 | Andrés García | 6 | 2028-2031 | |
| 18 | Cristóbal Hernández | 6 | 2027-2042 | |
| 18 | Aldo Hes | 6 | 2029-2034 | |
| 18 | Josh McDowell | 6 | 2030-2036 | |
| 18 | Ricardo Quadrado# | 6 | 2041-2052 | |
| 18 | Josh Taylor | 6 | 2025-2031 | |
| 18 | Luis Velásquez | 6 | 2025-2034 | |
| 18 | Anastasio Vázquez | 6 | 2025-2030 | |
| 18 | José Zúñiga | 6 | 2026-2033 | |
| 28 | Domingo Anaya | 5 | 2023-2030 | |
| 28 | Berndt Austerlitz | 5 | 2023-2030 | |
| 28 | Javier Bautista | 5 | 2024-2032 | |
| 28 | José Bray# | 5 | 2048-2058 | |
| 28 | Tony Caraballo | 5 | 2028-2037 | |
| 28 | Rafael Chávez | 5 | 2027-2035 | |
| 28 | Jorge Cintrón | 5 | 2027-2030 | |
| 28 | Carter Curtis | 5 | 2027-2032 | |
| 28 | Tommy Dietz | 5 | 2029-2037 | |
| 28 | Jeff Doane# | 5 | 2049-2053 | |
| 28 | Tanosuke Endo | 5 | 2045-2049 | |
| 28 | José Estrada | 5 | 2038-2038 | |
| 28 | Jesús Galván | 5 | 2019-2027 | |
| 28 | Luis Gonzáles | 5 | 2032-2041 | |
| 28 | François Mangin | 5 | 2036-2039 | |
| 28 | Dudley O'Connor | 5 | 2026-2026 | |
| 28 | Berhane Omondi | 5 | 2038-2050 | |
| 28 | Javier Parra# | 5 | 2055-2058 | |
| 28 | Vito Reyes | 5 | 2037-2043 | |
| 28 | Christopher Robinson | 5 | 2017-2027 | |
| 28 | Sergio Rojas | 5 | 2042-2051 | |
| 28 | Daisuke Tomita | 5 | 2022-2031 | |
| 28 | Randy Wood | 5 | 2024-2031 | |
| 28 | Barrett Woods | 5 | 2018-2031 | |
| 28 | In-sung Yi | 5 | 2039-2041 | |
| 53 | Juan Acevedo | 4 | 2022-2029 | |
| 53 | Jorge Aeyta | 4 | 2034-2042 | |
| 53 | Gabriel Alfonso | 4 | 2023-2035 | |
| 53 | Norm Alldritt# | 4 | 2050-2055 | |
| 53 | Stanley Benson | 4 | 2024-2031 | |
| 53 | Tony Canales | 4 | 2023-2040 | |
| 53 | Marcos Canavezes | 4 | 2027-2038 | |
| 53 | Roberto Cruz | 4 | 2028-2045 | |
| 53 | William Dawson | 4 | 2031-2045 | |
| 53 | Javier Delgado | 4 | 2022-2034 | |
| 53 | Elmer Foley | 4 | 2046-2052 | |
| 53 | Kevin Fowler | 4 | 2032-2037 | |
| 53 | Daniel González# | 4 | 2044-2052 | |
| 53 | Leonardo González# | 4 | 2049-2057 | |
| 53 | Jafar Haamid# | 4 | 2040-2055 | |
| 53 | James Heath | 4 | 2033-2047 | |
| 53 | C.J. Ischade | 4 | 2037-2046 | |
| 53 | Kenny Kelly# | 4 | 2045-2055 | |
| 53 | Ghi-cheng Kum | 4 | 2035-2053 | |
| 53 | Mario López | 4 | 2022-2037 | |
| 53 | Carlos Mata# | 4 | 2048-2058 | |
| 53 | Callum Maybury | 4 | 2035-2044 | |
| 53 | Mark McCray | 4 | 2032-2040 | |
| 53 | Gustavo Medina | 4 | 2022-2031 | |
| 53 | Hirotada Miura | 4 | 2031-2033 | |
| 53 | Sergio Montés | 4 | 2026-2034 | |
| 53 | Tony Morales | 4 | 2027-2033 | |
| 53 | José Méndez | 4 | 2022-2030 | |
| 53 | Johnny Nicholson# | 4 | 2051-2058 | |
| 53 | Xavier Pérez | 4 | 2035-2046 | |
| 53 | César Ramos | 4 | 2021-2031 | |
| 53 | Carlos Ramírez | 4 | 2024-2033 | |
| 53 | Ron Robert | 4 | 2029-2030 | |
| 53 | Arturo Rodríguez | 4 | 2021-2030 | |
| 53 | Héctor Romero | 4 | 2024-2029 | |
| 53 | Ryan Rose | 4 | 2033-2041 | |
| 53 | Héctor Soto | 4 | 2023-2025 | |
| 53 | Jaques Sucena | 4 | 2019-2029 | |
| 53 | Ricardo Sánchez | 4 | 2026-2027 | |
| 53 | Román Sánchez | 4 | 2037-2046 | |
| 53 | Vincente Sánchez | 4 | 2036-2040 | |
| 53 | Denny Tabb# | 4 | 2056-2058 | |
| 53 | Derrek Terry | 4 | 2034-2047 | |
| 53 | José Torres | 4 | 2033-2036 | |
| 53 | Masamune Ueda | 4 | 2035-2039 | |
| 53 | Corbin Valentín | 4 | 2041-2046 | |
| 53 | Ed Wearne# | 4 | 2051-2058 | |
| 53 | Bobby Wright# | 4 | 2050-2058 |
