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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Alfonso Castro | 65 | 2033-2038 | |
| 2 | Alfredo Gómez | 53 | 2049-2052 | |
| 2 | Felipe Martínez | 53 | 2036-2039 | |
| 4 | James Horton | 52 | 2003-2007 | |
| 5 | Rafael Pueblo | 51 | 2033-2038 | |
| 6 | Alonso Colón | 50 | 2014-2018 | |
| 6 | Nick Froelich | 50 | 2049-2052 | |
| 6 | Luis García | 50 | 2034-2038 | |
| 9 | Geoff Campbell | 48 | 2034-2039 | |
| 9 | Mack Collins | 48 | 2049-2052 | |
| 9 | Juan Muñóz | 48 | 2049-2052 | |
| 12 | Cori Connolly | 47 | 2029-2033 | |
| 12 | Albert Davis | 47 | 2049-2052 | |
| 12 | Colin Dixon | 47 | 2049-2052 | |
| 12 | Trent Kirkpatrick# | 47 | 2052-2057 | |
| 12 | Joe Livingston | 47 | 2016-2020 | |
| 12 | Jaime Tonche | 47 | 2003-2007 | |
| 12 | Alejandro Zamora | 47 | 2035-2039 | |
| 19 | Ernesto Cervantes | 46 | 2033-2038 | |
| 19 | Gabriel Chávez | 46 | 2003-2007 | |
| 19 | Yann Manfredi | 46 | 2005-2009 | |
| 19 | Alberto Menocchio | 46 | 2033-2038 | |
| 19 | Daniel Washington | 46 | 2012-2016 | |
| 24 | Josh Benez | 45 | 2004-2009 | |
| 24 | Miguel Bueno | 45 | 2033-2037 | |
| 24 | Norberto Navarro | 45 | 2050-2053 | |
| 24 | Claudio Núñez | 45 | 2008-2012 | |
| 24 | Carlos Ortíz | 45 | 2036-2040 | |
| 29 | Rafael Efignio | 44 | 2034-2038 | |
| 29 | Manuel Guzmán | 44 | 2009-2013 | |
| 29 | Dean Hollingsworth | 44 | 2031-2036 | |
| 29 | Marc McLean# | 44 | 2050-2053 | |
| 33 | Carl Boutin | 43 | 2034-2039 | |
| 33 | José Castillo | 43 | 2038-2041 | |
| 33 | Arnold Conley | 43 | 2031-2036 | |
| 33 | Jaime De Castillo | 43 | 2006-2009 | |
| 33 | Domingo Hernández | 43 | 2049-2052 | |
| 33 | Jorge Marino | 43 | 2036-2040 | |
| 33 | José Ojeda | 43 | 2033-2038 | |
| 33 | Jonathan Outhwaite | 43 | 2049-2052 | |
| 33 | Ramón Ramírez | 43 | 2010-2014 | |
| 33 | Paul Simpson | 43 | 2050-2052 | |
| 43 | José Aicón | 42 | 2005-2009 | |
| 43 | Sammer Bourguiba | 42 | 2033-2038 | |
| 43 | Alfredo Cavazos | 42 | 2033-2038 | |
| 43 | Randolph Dickerson | 42 | 2026-2032 | |
| 43 | Luis Gonzáles | 42 | 2032-2036 | |
| 43 | Torquato Leo | 42 | 2035-2039 | |
| 43 | Pedro Martínez | 42 | 2035-2039 | |
| 43 | Rafael Rivera | 42 | 2003-2007 | |
| 43 | Esteban Sánchez | 42 | 2011-2015 | |
| 43 | Joe West | 42 | 2005-2009 | |
| 53 | Máximo Antúnez | 41 | 2038-2041 | |
| 53 | Daniel Bailey | 41 | 2001-2004 | |
| 53 | Francis Brooks | 41 | 2049-2052 | |
| 53 | Francisco Contaldo | 41 | 2034-2039 | |
| 53 | Juan Flores | 41 | 2010-2014 | |
| 53 | Elvis Hewitt | 41 | 2034-2039 | |
| 53 | José Mejía | 41 | 2031-2037 | |
| 53 | Atsushi Ohashi | 41 | 2040-2043 | |
| 53 | Bill Rhodes | 41 | 2003-2007 | |
| 53 | Alberto Román | 41 | 2033-2038 | |
| 53 | Ricardo Salazar# | 41 | 2051-2053 | |
| 53 | Patrick Serrano | 41 | 2033-2037 | |
| 65 | Michael Bakke | 40 | 2050-2053 | |
| 65 | Ramón Castaneda | 40 | 2046-2049 | |
| 65 | Rafael Cuestas | 40 | 2003-2005 | |
| 65 | Juan García | 40 | 2016-2019 | |
| 65 | José Garza | 40 | 2036-2040 | |
| 65 | Esteban Gonzáles | 40 | 1999-2002 | |
| 65 | Ronald Hall | 40 | 2032-2037 | |
| 65 | Alfonso Martínez | 40 | 2034-2039 | |
| 65 | Ernesto Mata | 40 | 2034-2039 | |
| 65 | Alfredo Mora | 40 | 2002-2005 | |
| 65 | Martin Petersen | 40 | 2007-2011 | |
| 65 | Tony Riley | 40 | 2003-2007 | |
| 65 | Jeffrey Sprake | 40 | 2035-2039 | |
| 65 | Armando Vela# | 40 | 2052-2057 | |
| 79 | Jesús Anaya | 39 | 2033-2038 | |
| 79 | Francis Boyd | 39 | 2015-2018 | |
| 79 | James Brown | 39 | 2008-2011 | |
| 79 | Phil Carpenter# | 39 | 2049-2052 | |
| 79 | Martín Costello | 39 | 2034-2039 | |
| 79 | Phil Fleming | 39 | 2038-2040 | |
| 79 | Stephen Galloway | 39 | 2049-2052 | |
| 79 | Luciano Gonzáles | 39 | 2033-2037 | |
| 79 | Héctor Morán | 39 | 2016-2020 | |
| 79 | Sergio Pimentel# | 39 | 2053-2058 | |
| 79 | Mike Ramírez | 39 | 2016-2020 | |
| 79 | Duane Russell | 39 | 2008-2012 | |
| 79 | Fernando Salcedo | 39 | 2036-2039 | |
| 79 | Jason Sanders | 39 | 2048-2050 | |
| 79 | Blast Sullivan | 39 | 2030-2034 | |
| 79 | Pedro Ventura | 39 | 2003-2007 | |
| 95 | Carlos Acevedo | 38 | 2011-2015 | |
| 95 | Kieran Ash | 38 | 2050-2053 | |
| 95 | Francisco Bafana | 38 | 2008-2011 | |
| 95 | Habbo Bekema | 38 | 2012-2015 | |
| 95 | Bret Carter | 38 | 2011-2015 | |
| 95 | Millard Culbertson | 38 | 2049-2052 |
