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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Postseason Career Leaderboard |
|---|---|---|---|---|
| 1 | Yi-lin An | 0.000 | 2027 | |
| 1 | Alberto Chávez | 0.000 | 2049 | |
| 3 | Satoshi Shirai# | 0.321 | 2052 | |
| 4 | Tyler Rodríguez# | 0.380 | 2054 | |
| 4 | Nick Rivers# | 0.380 | 2053 | |
| 6 | Alejandro Cruz | 0.435 | 2052 | |
| 7 | Rafael Cruz | 0.466 | 2026 | |
| 8 | Luis Pérez# | 0.519 | 2051 | |
| 9 | Tso-lin Deng | 0.529 | 2039 | |
| 9 | Alejandro Cruz | 0.529 | 2051 | |
| 11 | Felipe Hernández | 0.574 | 2028 | |
| 12 | Marc Holby | 0.600 | 2053 | |
| 12 | Tarik Walliyullah# | 0.600 | 2058 | |
| 12 | Kane Wakelin | 0.600 | 2052 | |
| 15 | Mauro Flores | 0.614 | 2026 | |
| 16 | Félix Jiménez | 0.711 | 2039 | |
| 17 | Rick Goulding | 0.771 | 2049 | |
| 18 | Nolan Miller# | 0.900 | 2054 | |
| 19 | Daniel Ávila | 0.915 | 2040 | |
| 20 | Toshinobu Kiyomizu | 1.000 | 2047 | |
| 20 | Félix Jiménez | 1.000 | 2038 | |
| 22 | Josué Zúñiga | 1.059 | 2026 | |
| 22 | José Vázquez | 1.059 | 2041 | |
| 24 | Lance Barrett# | 1.080 | 2053 | |
| 25 | José Flores# | 1.125 | 2058 | |
| 26 | Álex León# | 1.141 | 2053 | |
| 27 | Fernando Gómez# | 1.174 | 2055 | |
| 28 | Lucas Black# | 1.200 | 2046 | |
| 28 | Jarred Perkins | 1.200 | 2037 | |
| 30 | Luis García# | 1.246 | 2054 | |
| 31 | Manuel Ruíz | 1.256 | 2048 | |
| 32 | Jeffrey Flowers# | 1.440 | 2050 | |
| 33 | Ross Brown# | 1.446 | 2047 | |
| 33 | Takafumi Ikeda | 1.446 | 2050 | |
| 33 | Dean O'Gribben# | 1.446 | 2046 | |
| 36 | Roger Guth | 1.500 | 2028 | |
| 36 | Pat Willard | 1.500 | 2037 | |
| 38 | Bill Keefe# | 1.521 | 2046 | |
| 39 | Nathan Thomas# | 1.558 | 2051 | |
| 39 | César De La Cruz | 1.558 | 2024 | |
| 41 | Monte Evans# | 1.588 | 2053 | |
| 41 | Bogdashha Melentiev | 1.588 | 2037 | |
| 43 | James Mullet | 1.612 | 2049 | |
| 44 | José Barrera | 1.620 | 2041 | |
| 45 | Ionel Ardeleanu# | 1.653 | 2056 | |
| 45 | Chris Rader# | 1.653 | 2054 | |
| 47 | Carlos Gallegos | 1.688 | 2037 | |
| 47 | José Macías | 1.688 | 2037 | |
| 47 | Alex Bohlen | 1.688 | 2040 | |
| 47 | Jarred Perkins | 1.688 | 2038 | |
| 51 | Alfonso Rodríguez# | 1.718 | 2057 | |
| 52 | Bob Coleman | 1.766 | 2030 | |
| 53 | Rodney Lester | 1.800 | 2055 | |
| 53 | Martín Castaneda | 1.800 | 2031 | |
| 53 | Wook-jin Pae | 1.800 | 2052 | |
| 53 | Aras Yilmanz | 1.800 | 2050 | |
| 57 | Roberto Lucero | 1.831 | 2046 | |
| 58 | José Lima# | 1.862 | 2057 | |
| 59 | Iván López | 1.929 | 2035 | |
| 60 | Alonso Amaya# | 1.964 | 2055 | |
| 60 | Dewey McKim# | 1.964 | 2055 | |
| 60 | Bartolo Caraballo# | 1.964 | 2056 | |
| 63 | David Carpenter | 1.969 | 2045 | |
| 64 | Shafgat Sabzvari# | 1.985 | 2057 | |
| 65 | Castel Pérez | 2.000 | 2036 | |
| 65 | José Hernández# | 2.000 | 2047 | |
| 65 | Pedro Sánchez | 2.000 | 2037 | |
| 68 | Jesse Jenkins# | 2.025 | 2048 | |
| 69 | Juan Sánchez | 2.077 | 2028 | |
| 69 | Owen Mcintyre# | 2.077 | 2054 | |
| 71 | Javier Salvao | 2.160 | 2030 | |
| 71 | Elias Agostinho | 2.160 | 2054 | |
| 71 | Luis Gonzáles | 2.160 | 2031 | |
| 74 | Alan Prowse | 2.172 | 2047 | |
| 75 | Marcos Hernández | 2.177 | 2035 | |
| 75 | Nick Rivers# | 2.177 | 2050 | |
| 77 | John Barber | 2.204 | 2051 | |
| 77 | Jackson Wear# | 2.204 | 2050 | |
| 79 | Nick Riddle | 2.250 | 2046 | |
| 79 | Brendan Walls | 2.250 | 2041 | |
| 79 | António Michel# | 2.250 | 2055 | |
| 82 | Niko Andric# | 2.298 | 2055 | |
| 83 | Mike James | 2.305 | 2050 | |
| 84 | Oswald Brenner | 2.314 | 2027 | |
| 85 | António Coztes | 2.348 | 2046 | |
| 85 | Mario Ríos | 2.348 | 2027 | |
| 87 | Edwin Gilliam | 2.362 | 2033 | |
| 88 | Luigi Ahern | 2.400 | 2040 | |
| 88 | Ángel González | 2.400 | 2039 | |
| 90 | Jesús Duarte | 2.427 | 2026 | |
| 91 | Javier López# | 2.455 | 2056 | |
| 91 | Xing-fu Bao | 2.455 | 2054 | |
| 91 | Vicente Osorio | 2.455 | 2045 | |
| 94 | Shotaro Kawamura | 2.492 | 2033 | |
| 94 | Keizo Kaneko | 2.492 | 2040 | |
| 96 | Juan Pérez | 2.531 | 2036 | |
| 96 | Wilson Rivera# | 2.531 | 2058 | |
| 98 | Clay Stabb# | 2.571 | 2056 | |
| 98 | José Costello# | 2.571 | 2046 | |
| 100 | Jimmy Greenwood | 2.596 | 2024 |
