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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Holden Dickson | 180 | 2042-2053 | |
| 2 | António Méndez | 141 | 2032-2043 | |
| 3 | Alejandro Rodríguez | 138 | 2036-2050 | |
| 4 | Virginia Rain | 123 | 2042-2055 | |
| 5 | Eduardo Montoya | 122 | 2017-2026 | |
| 6 | Bill Wilkins | 119 | 2033-2043 | |
| 7 | Brendan Kerndl | 115 | 2034-2047 | |
| 8 | Doug Glover, Jr. | 114 | 2034-2043 | |
| 9 | Dan Norman | 113 | 2031-2041 | |
| 10 | Larry Petty | 111 | 2019-2027 | |
| 11 | Will Nelson | 110 | 2048-2055 | |
| 12 | Júlio Montoya | 108 | 2033-2042 | |
| 13 | Xavier Álvarez | 101 | 2031-2039 | |
| 14 | Jorge Estrada | 92 | 2042-2052 | |
| 14 | Domingo Valdés | 92 | 2041-2047 | |
| 16 | Roberto Nieves | 91 | 2024-2033 | |
| 17 | Alfredo Padilla | 89 | 2037-2042 | |
| 18 | Félix Ladaga# | 88 | 2051-2056 | |
| 19 | Adrián Ramos | 87 | 2039-2043 | |
| 20 | Luis Hernández | 86 | 2022-2026 | |
| 20 | Jamie Murray | 86 | 2024-2032 | |
| 20 | Chuck Pate | 86 | 2023-2032 | |
| 23 | Gerardo López | 84 | 2032-2038 | |
| 23 | Jim Tremblett | 84 | 2030-2040 | |
| 23 | Alfredo Velázquez | 84 | 2030-2036 | |
| 26 | Tom Coulthard | 83 | 2031-2038 | |
| 26 | David Graham | 83 | 2050-2053 | |
| 28 | Mason Carter | 81 | 2011-2018 | |
| 29 | Mitchell Cashmore# | 80 | 2047-2058 | |
| 30 | Neil Brickell | 79 | 2034-2041 | |
| 30 | Cristo Coronado | 79 | 2027-2039 | |
| 30 | Jayson Weber | 79 | 2021-2030 | |
| 33 | José Díaz# | 78 | 2044-2052 | |
| 34 | Adam Riggs# | 77 | 2045-2058 | |
| 34 | José Toledo | 77 | 2039-2046 | |
| 36 | Pedro Nava | 76 | 2031-2043 | |
| 37 | Jim Green | 75 | 2030-2036 | |
| 38 | Nicholas Salazar | 74 | 2034-2041 | |
| 39 | Gilberto Crus | 73 | 2041-2046 | |
| 39 | Héctor Ojeda | 73 | 2042-2052 | |
| 39 | Wilton Sanders | 73 | 2018-2032 | |
| 39 | Kazuo Yamamoto | 73 | 2034-2039 | |
| 43 | Don Hattie# | 72 | 2046-2054 | |
| 43 | Pat Holland | 72 | 2032-2037 | |
| 45 | Juan Hernández | 71 | 2044-2054 | |
| 46 | Brian Horn | 70 | 2032-2039 | |
| 47 | Jenbere Garang | 69 | 2035-2040 | |
| 47 | Mark Vincent | 69 | 2022-2028 | |
| 49 | Luis Alvarado | 68 | 2019-2032 | |
| 50 | J.R. Browne# | 67 | 2044-2054 | |
| 50 | Dan Reed | 67 | 2036-2042 | |
| 52 | Clarence Kirkpatrick | 66 | 2036-2043 | |
| 52 | Emílio Medina | 66 | 2041-2050 | |
| 54 | Derek Lee | 65 | 2029-2037 | |
| 54 | Dave Quinn | 65 | 2006-2018 | |
| 56 | Javier Bultrón | 64 | 2040-2054 | |
| 56 | Alfonso Espinosa | 64 | 2013-2025 | |
| 56 | Jim Walker | 64 | 2015-2023 | |
| 59 | Wllibald Akbulut | 63 | 2040-2057 | |
| 60 | Jorge Canó# | 62 | 2056-2057 | |
| 60 | Jaime Valle | 62 | 2016-2023 | |
| 60 | Richard Wright# | 62 | 2050-2055 | |
| 60 | Leyli Yelanian | 62 | 2030-2045 | |
| 64 | Alfonso Ibáñez | 61 | 2024-2027 | |
| 64 | Ed Ward | 61 | 2017-2022 | |
| 66 | Víctor Bedolla | 60 | 2033-2043 | |
| 66 | Willie Carter | 60 | 2033-2047 | |
| 66 | António Colomo | 60 | 2027-2032 | |
| 66 | Enrico González | 60 | 2004-2013 | |
| 70 | Logan Bannon | 59 | 2050-2054 | |
| 70 | Ramiro Cordero | 59 | 2045-2050 | |
| 70 | Tomás Durán | 59 | 2040-2053 | |
| 73 | Carlos Acevedo | 58 | 2046-2052 | |
| 73 | José Benavidez | 58 | 2041-2050 | |
| 73 | Mark Rich | 58 | 2033-2039 | |
| 76 | Brian Corrigan | 57 | 2015-2022 | |
| 76 | Robert Hooper# | 57 | 2051-2058 | |
| 76 | Kevin Hughes | 57 | 2028-2035 | |
| 76 | Ben Ruzic | 57 | 2050-2054 | |
| 80 | Bruce Hillier# | 56 | 2053-2057 | |
| 80 | Callum Hopkins | 56 | 2014-2025 | |
| 82 | Santiago Greene | 55 | 2016-2020 | |
| 82 | Anastasio Guillén# | 55 | 2041-2052 | |
| 82 | Rio North | 55 | 2032-2037 | |
| 82 | Ricardo Onelas | 55 | 2022-2027 | |
| 82 | Adão Yoshida | 55 | 2054-2057 | |
| 87 | Carlos Alonso | 54 | 2042-2047 | |
| 87 | Chris Limón | 54 | 2029-2044 | |
| 87 | Anthony Moretti# | 54 | 2047-2056 | |
| 87 | Rodger Rutherford# | 54 | 2053-2057 | |
| 91 | Raymond Aguilera | 53 | 2026-2039 | |
| 91 | Ricardo Aragón | 53 | 2036-2053 | |
| 91 | Kenny Blackwell# | 53 | 2048-2052 | |
| 91 | Mike Galloway | 53 | 2052-2056 | |
| 91 | Francisco Moreno | 53 | 2018-2029 | |
| 96 | Bryan Morris | 52 | 2023-2027 | |
| 97 | Dave Bane | 51 | 2033-2037 | |
| 97 | Ángel Hernández | 51 | 2024-2027 | |
| 97 | Shane Wilkinson | 51 | 2047-2050 | |
| 100 | Stephen Ireland | 50 | 2015-2018 |
